The specificity and efficacy of alternating electric fields as a prospective cancer treatment

Palupi, Endah Sri and Retnoaji, Bambang and Astuti, Pudji and Alamsyah, Firman and Pratiwi, Rarastoeti (2023) The specificity and efficacy of alternating electric fields as a prospective cancer treatment. ASM Science Journal, 18. pp. 1-14. ISSN 1823-6782

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An external electric field is still debatable for cancer treatment, although many study results proved its capacity. Cancer involves complex mechanisms, including how the cancer cells arise and grow. Thus, this disease is known to have many hallmarks. This condition complicates precise and accurate treatment. The study proved that an external electric field has prospects to become an effective cancer treatment, demonstrated by its ability to inhibit cancer growth through anti-proliferative and pro-apoptotic capacities. Several devices generating electric fields for cancer treatment were Tumour Treating Fields (TTFields), nanosecond Pulsed Electric Fields (nsPEF), picosecond Pulsed Electric Fields (psPEF), and Electro-Capacitive Cancer Therapy (ECCT). This article will compare those devices’ efficacy, safety, treatment methods, and research progress, including the advantages and disadvantages of static electric field devices and future research prospects. More attention will be focused on ECCT, which has been closely and profoundly investigated in breast cancer treatment.

Item Type: Article
Uncontrolled Keywords: AC source; anti-cancer; anti-mitotic; electric fields; pro-apoptotic
Subjects: 500 Natural sciences & mathematics > 570 Life sciences (Biology)
600 Applied sciences & technology > 610 Medicine & health > 616 Diseases
Divisions: Universitas Al-Azhar Indonesia (UAI) > Fakultas Sains dan Teknologi (FST) > Biologi
Depositing User: Rifda Jilan
Date Deposited: 12 Feb 2024 07:32
Last Modified: 12 Feb 2024 07:55

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